Article
Head circumference, apolipoprotein E genotype and cognition in the Bavarian School Sisters Study.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Apr 2012
Perneczky R, Alexopoulos P, Wagenpfeil S, Bickel H, Kurz A
Abstract excerpt
BACKGROUND: The apolipoprotein E (APOE) ɛ4 allele is correlated with an earlier onset of Alzheimer's disease symptoms; larger head circumference has been associated with an individual resilience against cognitive impairment. METHODS: We explored if larger head circumference attenuates the effect of the APOE ɛ4 allele on cognition in 380 Catholic sisters covering the spectrum from normal cognitive performance to...
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