Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new interaction between SLC6A4 variation and child abuse is associated with resting heart rate.

Depression and anxiety - 1 Mar 2011

Shinozaki Gen, Romanowicz Magdalena, Kung Simon, Mrazek David A

Abstract excerpt

BACKGROUND: The short form of the indel promoter polymorphism (5HTTLPR) of the serotonin transporter gene (SLC6A4) and a history of child abuse have been reported to be associated with an increased risk for the development of depression. A child abuse history has also been associated with more ra...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arousal
Share to Child Abuse
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Heart Rate

Share to Homozygote

Share to Serotonin Plasma Membrane Transport Proteins

Share to Statistics as Topic

Source

Identifiers

PMID: 21394855
DOI: 10.1002/da.20779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21394855-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new interaction between SLC6A4 variation and child abuse is associated with resting heart rate.PMID 21394855Read ↗

HTR2A gene-child abuse interaction and association with a history of suicide attempt among Caucasian depressed psychiatric inpatients.Semantic proximity Read ↗

Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children.Semantic proximity Read ↗

Interaction among childhood trauma and functional polymorphisms in the serotonin pathway moderate the risk of depressive disorders.Semantic proximity Read ↗

Serotonin transporter (5-HTTLPR) genotype, childhood abuse, and suicide attempts in adult psychiatric inpatients.Semantic proximity Read ↗

Serotonin transporter length polymorphism, childhood maltreatment, and chronic depression: a specific gene-environment interaction.Semantic proximity Read ↗

Associations between the SS variant of 5-HTTLPR and PTSD among adults with histories of childhood emotional abuse: results from two African American independent samples.Semantic proximity Read ↗

Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms.Semantic proximity Read ↗

5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder.Semantic proximity Read ↗

Life stressors and 5-HTTLPR interaction in relation to midpregnancy depressive symptoms among African-American women.Semantic proximity Read ↗

Prenatal exposure to serotonin reuptake inhibitors and congenital heart anomalies: an exploratory pharmacogenetics study.Semantic proximity Read ↗

[Association between serotonin transporter and monoamine oxidase A gene polymorphisms and depression].Semantic proximity Read ↗

Association between the serotonin transporter triallelic genotype and eating problems is moderated by the experience of childhood trauma in women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.