Article
TMPRSS2/ERG fusion gene expression alters chemo- and radio-responsiveness in cell culture models of androgen independent prostate cancer.
The Prostate - 1 Oct 2011
Swanson Todd A, Krueger Sarah A, Galoforo Sandra, Thibodeau Bryan J, Martinez Alvaro A, Wilson George D, Marples Brian
Abstract excerpt
PURPOSE/OBJECTIVES: The androgen regulated transmembrane serine protease (TMPRSS2) and ETS transcription factor (ERG) gene fusion is a strong prognostic factor for disease recurrence following prostatectomy. Expression of TMPRSS2/ETS-related gene (ERG) fusion gene transcripts is linked with tumor...
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