Article
Growth-phase dependence of susceptibility to antimicrobial peptides in Staphylococcus aureus.
Microbiology (Reading, England) - 1 Jun 2011
Matsuo Miki, Oogai Yuichi, Kato Fuminori, Sugai Motoyuki, Komatsuzawa Hitoshi
Abstract excerpt
Bacterial cell surface charge is responsible for susceptibility to cationic antimicrobial peptides. Previously, Staphylococcus aureus dlt and mprF were identified as factors conferring a positive charge upon cell surfaces. In this study, we investigated the regulation of cell surface charge during growth. Using a group of S. aureus MW2 mutants, which are gene-inactivated in 15 types of two-component systems...
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