Article
Comparison of 2 line blot assays for defining HPV genotypes in oral and oropharyngeal squamous cell carcinomas.
Diagnostic microbiology and infectious disease - 1 Jun 2011
Shanesmith Rebecca, Allen Richard A, Moore William E, Kingma Douglas W, Caughron Samuel K, Gillies Elizabeth M, Dunn Samuel T
Abstract excerpt
Patients with invasive oral and oropharyngeal squamous cell carcinomas infected with human papillomaviruses (HPV) demonstrate improved survival. HPV detection in tumors may assist in risk stratification of patients and in guiding optimum treatment. Two reverse line blot assays [Linear Array (LA) and INNO-LiPA (LiPA)] were evaluated for detection of HPV genotypes in paraffin-embedded biopsies. Overall, 82.4% of...
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