Article
HPV genotypes in high grade cervical lesions and invasive cervical carcinoma as detected by two commercial DNA assays, North Carolina, 2001-2006.
PloS one - 1 Jan 2012
Hariri Susan, Steinau Martin, Rinas Allen, Gargano Julia W, Ludema Christina, Unger Elizabeth R, Carter Alicia L, Grant Kathy L, Bamberg Melanie, McDermott James E, Markowitz Lauri E, Brewer Noel T, Smith Jennifer S
Abstract excerpt
BACKGROUND: HPV typing using formalin fixed paraffin embedded (FFPE) cervical tissue is used to evaluate HPV vaccine impact, but DNA yield and quality in FFPE specimens can negatively affect test results. This study aimed to evaluate 2 commercial assays for HPV detection and typing using FFPE cervical specimens. METHODS: Four large North Carolina pathology laboratories provided FFPE specimens from 299 women...
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