Article
Detection of HPV DNA in paraffin-embedded cervical samples: a comparison of four genotyping methods.
BMC infectious diseases - 25 Nov 2015
Castro Felipe A, Koshiol Jill, Quint Wim, Wheeler Cosette M, Gillison Maura L, Vaughan Laurence M, Kleter Bernhard, van Doorn Leen-Jan, Chaturvedi Anil K, Hildesheim Allan, Schiffman Mark, Wang Sophia S, Zuna Rosemary E, Walker Joan L, Dunn S Terence, Wentzensen Nicolas
Abstract excerpt
BACKGROUND: Identification of human papillomavirus (HPV) DNA in cervical tissue is important for understanding cervical carcinogenesis and for evaluating cervical cancer prevention approaches. However, HPV genotyping using formalin-fixed, paraffin-embedded (FFPE) tissues is technically challenging. We evaluated the performance of four commonly used genotyping methods on FFPE cervical specimens conducted in...
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