Article
Coupled modelling of tumour angiogenesis, tumour growth and blood perfusion.
Journal of theoretical biology - 21 Jun 2011
Cai Yan, Xu Shixiong, Wu Jie, Long Quan
Abstract excerpt
We propose a mathematical modelling system to investigate the dynamic process of tumour cell proliferation, death and tumour angiogenesis by fully coupling the vessel growth, tumour growth and blood perfusion. Tumour growth and angiogenesis are coupled by the chemical microenvironment and the cell-matrix interaction. The haemodynamic calculation is carried out on the updated vasculature. The domains of...
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