Article
A hybrid multiscale model for investigating tumor angiogenesis and its response to cell-based therapy.
In silico biology - 1 Jan 2019
Hendrata Melisa, Sudiono Janti
Abstract excerpt
Angiogenesis, a formation of blood vessels from an existing vasculature, plays a key role in tumor growth and its progression into cancer. The lining of blood vessels consists of endothelial cells (ECs) which proliferate and migrate, allowing the capillaries to sprout towards the tumor to deliver the needed oxygen. Various treatments aiming to suppress or even inhibit angiogenesis have been explored. Mesenchymal...
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