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Article

"Dynamic range" of inferred phenotypic HIV drug resistance values in clinical practice.

PloS one - 24 Feb 2011

Swenson Luke C, Pollock Graham, Wynhoven Brian, Mo Theresa, Dong Winnie, Hogg Robert S, Montaner Julio S G, Harrigan P Richard

Abstract excerpt

BACKGROUND: 'Virtual' or inferred phenotypes (vPhenotypes) are commonly used to assess resistance to antiretroviral agents in patients failing therapy. In this study, we provide a clinical context for understanding vPhenotype values. METHODS: All HIV-infected persons enrolled in the British Columbia Drug Treatment Program with a baseline plasma viral load (pVL) and follow-up genotypic resistance and pVL results...

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Topics

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Share to Anti-HIV Agents
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Forecasting

Share to Nonlinear Dynamics

Share to Practice Patterns, Physicians'

Share to Treatment Failure

Share to Viral Load

Source

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Identifiers

PMID: 21390218
DOI: 10.1371/journal.pone.0017402
PMCID: PMC3044728

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