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Article

Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells.

PloS one - 28 Feb 2011

Hewitt Kyle J, Shamis Yulia, Hayman Ryan B, Margvelashvili Mariam, Dong Shumin, Carlson Mark W, Garlick Jonathan A

Abstract excerpt

Human induced pluripotent stem (hiPS) cells offer a novel source of patient-specific cells for regenerative medicine. However, the biological potential of iPS-derived cells and their similarities to cells differentiated from human embryonic stem (hES) cells remain unclear. We derived fibroblast-like cells from two hiPS cell lines and show that their phenotypic properties and patterns of DNA methylation were...

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Identifiers

PMID: 21386890
DOI: 10.1371/journal.pone.0017128
PMCID: PMC3046119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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