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Article

Inferring population decline and expansion from microsatellite data: a simulation-based evaluation of the Msvar method.

Genetics - 1 May 2011

Girod Christophe, Vitalis Renaud, Leblois Raphaël, Fréville Hélène

Abstract excerpt

Reconstructing the demographic history of populations is a central issue in evolutionary biology. Using likelihood-based methods coupled with Monte Carlo simulations, it is now possible to reconstruct past changes in population size from genetic data. Using simulated data sets under various demographic scenarios, we evaluate the statistical performance of Msvar, a full-likelihood Bayesian method that infers past...

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Identifiers

PMID: 21385729
DOI: 10.1534/genetics.110.121764
PMCID: PMC3120153

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