Article
Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution.
Epidemiology (Cambridge, Mass.) - 1 Mar 2010
Ren Cizao, Park Sung Kyun, Vokonas Pantel S, Sparrow David, Wilker Elissa, Baccarelli Andrea, Suh Helen H, Tucker Katherine L, Wright Robert O, Schwartz Joel
Abstract excerpt
BACKGROUND: Ambient particles are associated with cardiovascular events and recently with total plasma homocysteine. High total plasma homocysteine is a risk for human health. However, the biologic mechanisms are not fully understood. One of the putative pathways is through oxidative stress. We aimed to examine whether associations of PM2.5 and black carbon with homocysteine were modified by genotypes including...
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