Article
Mitochondrial C150T polymorphism increases the risk of cervical cancer and HPV infection.
Mitochondrion - 1 Jul 2011
Zhai Kan, Chang Lihong, Zhang Qingming, Liu Benrong, Wu Yuping
Abstract excerpt
During a survey of control region (D-loop) sequence variances in 142 cervical cancer (CC) patients and 136 controls, all Chinese women, including both HPV-positive (human papillomavirus) and HPV-negative subjects, we determined that the C150T polymorphism increased the CC risk in a case-control study (OR=3.0, 95% CI=1.8-5.0, P<0.05). HPV-positive individuals were more likely to carry the C150T polymorphism than...
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