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Article

Cytokine‐related syndrome following injection of anti‐CD3 monoclonal antibody: Further evidence for transient <i>in vivo</i> T cell activation

1 Mar 1990

Abstract excerpt

In vivo injection of the hamster anti-murine CD3 monoclonal antibody 145 2C11 into BALB/c mice induces a massive systemic release of several cytokines. Very high circulating levels of tumor necrosis factor are detected both by enzyme-linked immunosorbent assay and L-929 bioassay 90 min following a single injection of 10 micrograms/mouse 145 2C11. Peak circulating levels of exclusively T cell-derived products such...

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PMID: 2138557
DOI: 10.1002/eji.1830200308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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