Article
Congenital heart defects and maternal genetic, metabolic, and lifestyle factors.
Birth defects research. Part A, Clinical and molecular teratology - 1 Apr 2011
Hobbs Charlotte A, MacLeod Stewart L, Jill James S, Cleves Mario A
Abstract excerpt
BACKGROUND: The purpose of this study was to identify metabolic, genetic, and lifestyle factors that discriminate between women who have pregnancies affected by congenital heart defects (CHDs) from those who have unaffected pregnancies. METHODS: We analyzed the concentrations of 13 serum biomarkers, 3 functional genetic variants, and 4 lifestyle factors among 417 women with CHD-affected pregnancies and 250...
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