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Comparative analysis on the membrane proteome of Clostridium acetobutylicum wild type strain and its butanol-tolerant mutant.

Molecular bioSystems - 1 May 2011

Mao Shaoming, Luo Yuanming, Bao Guanhui, Zhang Yanping, Li Yin, Ma Yanhe

Abstract excerpt

The solventogenic bacterium Clostridium acetobutylicum is the most important species of Clostridium used in the fermentation industry. However, the intolerance to butanol hampers the efficient production of solvents. Butanol toxicity has been attributed to the chaotropic effect on the cell membrane, but the knowledge on the effect of butanol on membrane associated proteins is quite limited. Using 2-DE combined...

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PMID: 21384033
DOI: 10.1039/c0mb00330a

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