Article
Comparative genomic and proteomic analyses of Clostridium acetobutylicum Rh8 and its parent strain DSM 1731 revealed new understandings on butanol tolerance.
Biochemical and biophysical research communications - 8 Aug 2014
Bao Guanhui, Dong Hongjun, Zhu Yan, Mao Shaoming, Zhang Tianrui, Zhang Yanping, Chen Zugen, Li Yin
Abstract excerpt
Clostridium acetobutylicum strain Rh8 is a butanol-tolerant mutant which can tolerate up to 19g/L butanol, 46% higher than that of its parent strain DSM 1731. We previously performed comparative cytoplasm- and membrane-proteomic analyses to understand the mechanism underlying the improved butanol tolerance of strain Rh8. In this work, we further extended this comparison to the genomic level. Compared with the...
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