Article
Targeting the hallmarks of cancer
16 Nov 2012
Abstract excerpt
In 2000, Hanahan and Weinberg [1] proposed that the remarkable diversity of neoplastic diseases and of their underlying molecular mechanisms could be rationalized into six biological processes that, together, constitute the molecular and cellular infrastructure of cancer, thus identifying the ‘Hallmarks of Cancer’. To the six initial Hallmarks’ processes (sustaining proliferative signalling, evading growth...
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