Article
Oral Streptococci and Cardiovascular Disease: Searching for the Platelet Aggregation‐Associated Protein Gene and Mechanisms of <i>Streptococcus sanguis</i>‐Induced Thrombosis
1 Nov 2005
Abstract excerpt
BACKGROUND: Pathogenic mechanisms in infective endocarditis, disseminated intravascular coagulation, and cardiovascular events involve the aggregation of platelets into thrombi. Attendant infection by oral bacteria contributes to these diseases. We have been studying how certain oral streptococci induce platelet aggregation in vitro and in vivo. Streptococcus sanguis expresses a platelet aggregation-associated...
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