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Article

Keratinocytes Are Cell Targets of West Nile Virus <i>In Vivo</i>

4 Mar 2011

Abstract excerpt

West Nile virus (WNV) replicates in the skin; however, cell targets in the skin have not been identified. In the current studies, WNV infected the epidermis and adnexal glands of mouse skin, and the epidermal cells were identified as keratinocytes by double labeling for WNV antigen and keratin 10. Inoculation of mice with WNV replicon particles resulted in high levels of replication in the skin, suggesting that...

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PMID: 21367890
DOI: 10.1128/jvi.02692-10

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