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Article

The rno‐miR‐34 family is upregulated and targets ACSL1 in dimethylnitrosamine‐induced hepatic fibrosis in rats

3 Mar 2011

Abstract excerpt

The mechanisms whereby hepatic fibrosis develops in chronic liver diseases remain incompletely defined. Here, we sought to examine whether microRNA (miRNA) became dysregulated in dimethylnitrosamine-induced hepatic fibrosis in rats. Our microarray analysis revealed that the miR-34 family was upregulated along with other miRNAs in liver fibrotic tissues. Six miRNAs, such as rno-miR-878, were downregulated. The...

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PMID: 21366874
DOI: 10.1111/j.1742-4658.2011.08075.x

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