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Article

The Progression of Liver Fibrosis Is Related with Overexpression of the miR-199 and 200 Families

24 Jan 2011

Abstract excerpt

BACKGROUND: Chronic hepatitis C (CH) can develop into liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Liver fibrosis and HCC development are strongly correlated, but there is no effective treatment against fibrosis because the critical mechanism of progression of liver fibrosis is not fully understood. microRNAs (miRNAs) are now essential to the molecular mechanisms of several biological processes. In...

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PMID: 21283674
DOI: 10.1371/journal.pone.0016081

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