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Article

MicroRNA profiles following metformin treatment in a mouse model of non-alcoholic steatohepatitis

6 Feb 2015

Abstract excerpt

Non-alcoholic steatohepatitis (NASH) is one of the most common causes of chronic liver disease and is considered to be a causative factor of cryptogenic cirrhosis and hepatocellular carcinoma. microRNAs (miRNAs) are small non-coding RNAs that negatively regulate messenger RNA (mRNA). Recently, it was demonstrated that the aberrant expression of certain miRNAs plays a pivotal role in liver disease. The aim of the...

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PMID: 25672270
DOI: 10.3892/ijmm.2015.2092

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