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Article

Modulation of urinary polycyclic aromatic hydrocarbon metabolites by enzyme polymorphisms in workers of the German Human Bitumen Study.

Archives of toxicology - 1 Jun 2011

Rihs Hans-Peter, Spickenheuer Anne, Heinze Evelyn, Pesch Beate, Raulf-Heimsoth Monika, Angerer Jürgen, Brüning Thomas

Abstract excerpt

Data concerning the influence of sequence variants of metabolizing enzymes on the effect modulation of current exposure to vapors and aerosols of bitumen in humans are limited. To assess the influence of 18 single-nucleotide polymorphisms (SNP) in genes coding for enzymes involved in polycyclic aromatic hydrocarbon (PAH) and amine metabolism regarding their impact on urinary markers 1-hydroxpyrene (1-OHP) and the...

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Source

Identifiers

PMID: 21359562
DOI: 10.1007/s00204-011-0684-3

Genes

NAT2
PAH
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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