Article
M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis.
The American journal of pathology - 1 Mar 2011
Prokop Stefan, Heppner Frank L, Goebel Hans H, Stenzel Werner
Abstract excerpt
The etiopathogenesis of sarcoidosis, a systemic granulomatous disease, still remains obscure. A multitude of organs have been described to be affected in systemic sarcoidosis. Skeletal muscles may also be affected, leading to myalgia and weakness. A workup of the specific immune response with emphasis on the macrophage response is provided herein. Affected muscle tissue from seven patients with systemic...
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