Article
Control of lifespan by food bacteria, nutrient limitation and pathogenicity of food in C. elegans.
Mechanisms of ageing and development - 1 Apr 2011
So Shuhei, Tokumaru Takaaki, Miyahara Kohji, Ohshima Yasumi
Abstract excerpt
The increased lifespan caused by food limitation has been observed in a wide range of animals including the nematode Caenorhabditis elegans. We show here that the lifespans of eat-2 and eat-5 feeding-defective mutants and a mutant of dbl-1 encoding a TGFβ ligand significantly change between the cultures fed on Escherichia coli strain OP50 or a more nutrient-rich strain HB101. On HB101 food, the eat-2, eat-5 and...
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