From pathogen to a commensal: modification of the Microbacterium nematophilum-Caenorhabditis elegans interaction during chronic infection by the absence of host insulin signalling.

Abstract excerpt

The nematode worm Caenorhabditis elegans depends on microbes in decaying vegetation as its food source. To survive in an environment rich in opportunistic pathogens, Celegans has evolved an epithelial defence system where surface-exposed tissues such as epidermis, pharynx, intestine, vulva and hindgut have the capacity of eliciting appropriate immune defences to acute gut infection. However, it is unclear how the...

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• Caenorhabditis elegans
• Caenorhabditis elegans Proteins
• Forkhead Transcription Factors
• Gram-Positive Bacterial Infections
• Host-Pathogen Interactions