Article
Impact of bezafibrate and atorvastatin on lipoprotein subclass in patients with type III hyperlipoproteinemia: result from a crossover study.
Clinica chimica acta; international journal of clinical chemistry - 12 May 2011
Kawashiri Masa-aki, Kobayashi Junji, Nohara Atsushi, Noguchi Tohru, Tada Hayato, Nakanishi Chiaki, Inazu Akihiro, Mabuchi Hiroshi, Yamagishi Masakazu
Abstract excerpt
BACKGROUND: We elucidated the difference between the effects of bezafibrate and atorvastatin in hypertriglyceridemia with apoE2/2 and 3/3. METHODS: An open randomized crossover study consisted of a 4-week treatment period with bezafibrate (400 mg daily) or atorvastatin (10 mg daily) and a 4-week wash-out period. RESULTS: Bezafibrate significantly decreased serum concentrations of triglyceride (apoE2/2, E3/3:...
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