Article
Phenotype-dependent and -independent actions of rosuvastatin on atherogenic lipoprotein subfractions in hyperlipidaemia.
Atherosclerosis - 1 Dec 2003
Caslake Muriel J, Stewart Grace, Day Stephen P, Daly Elaine, McTaggart Fergus, Chapman M John, Durrington Paul, Laggner Peter, Mackness Michael, Pears John, Packard Chris J
Abstract excerpt
This randomised, double-blind, placebo-controlled crossover study evaluated the effects of rosuvastatin (40 mg/day for 8 weeks) on atherogenic apolipoprotein B-containing lipoprotein subfractions. Subjects, recruited based on raised plasma triglyceride (TG) or low-density lipoprotein cholesterol (LDL-C), were divided into normotriglyceridaemic (NTG, n = 13; TG < 2.0 mmol/l) and hypertriglyceridaemic (HTG, n = 16;...
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