Article
[Biochemical screening and genetic diagnosis of thalassemia in children from Kunming].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Feb 2011
Wen Bai-Ping, Fan Mao, Dai Hong-Jian, Zhuang Yu, Liu Hong-Ling, Yang Jun-Yi, Yang Xiao-Hong, Deng Wen-Guo
Abstract excerpt
OBJECTIVE: To investigate the types and frequency of gene mutations in children with thalassemia in Kunming, Yunan Province. METHODS: A biochemical screening for thalassemia was performed by testing RBC fragility, MCV and hemoglobin electrophoresis on 1338 children from Kunming, Yunnan Province. Genetic diagnosis was performed on the children with α-thalassemia by gap-PCR and on the children with β-thalassemia by...
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