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[Analysis of the Types of Thalassemia Gene Mutations in Nanping Area of Fujian, China].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2020

Chen Ming-Fa, Huang Min-Zhong, Lin Quan, Huang Jia, Chen Fang, Zhang Jia-Ying, Xue Fei

Abstract excerpt

OBJECTIVE: To investigation the types and frequencies of thalassemia gene mutations in pregnant population in Nanping area of Fujian Province, so as to provide a basis for prevention and control of birth children with moderate and severe thalassaemia in this area. METHODS: The genotyping of α and β thalassemia was performed using the gap-PCR (gap-PCR) technique combined with reverse dot blot (RDB). The genotyping...

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PMID: 32552958
DOI: 10.19746/j.cnki.issn.1009-2137.2020.03.033

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