Article
[Gene Analysis of Thalassemia in Han and Dai Ethnic Childbearing-aged Population of Chinese Yunnan Province].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2016
He Jing, Zeng Xiao-Hong, Xu Yong-Mei, Pu Jian, Zhou Feng-Zhen, Jin Chan-Chan, Su Jie, Zhang Jin-Man, Chen Hong, Zhang Jie, Li Sun-Yun, Zhang Yin-Hong, Zhu Bao-Sheng
Abstract excerpt
OBJECTIVE: To investigate the common mutation spectrum of α- and β-thalassemia in Yunnan childbearing-aged population. METHODS: The common mutation types of α- or β-globin genes were detected by multiple Gap-PCR and the PCR-reversed dot blotting, and the unknown mutation types were determined by DNA sequencing in DNA samples of hypochromic microcytic anemia patients and carriers who were confirmed to be positive...
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