Article
Genetic polymorphisms in Na+-taurocholate co-transporting polypeptide (NTCP) and ileal apical sodium-dependent bile acid transporter (ASBT) and ethnic comparisons of functional variants of NTCP among Asian populations.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Jun 2011
Pan Wei, Song Im-Sook, Shin Ho-Jung, Kim Min-Hye, Choi Yeong-Lim, Lim Su-Jeong, Kim Woo-Young, Lee Sang-Seop, Shin Jae-Gook
Abstract excerpt
Genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP; SLC10A1) and ileal apical sodium-dependent bile acid transporter (ASBT; SLC10A2), which greatly contribute to bile acid homeostasis, were extensively explored in the Korean population and functional variants of NTCP were compared among Asian populations. From direct DNA sequencing, six SNPs were identified in the SLC10A1 gene and 14 SNPs in...
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