Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a NBD1-Binding Pharmacological Chaperone that Corrects the Trafficking Defect of F508del-CFTR

1 Feb 2011

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Genetics and Biotechnology
Share to Cystic Fibrosis Research Advances
Share to Endoplasmic Reticulum Stress and Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21338920
DOI: 10.1016/j.chembiol.2010.11.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a NBD1-Binding Pharmacological Chaperone that Corrects the Trafficking Defect of F508del-CFTRPMID 21338920Read ↗

Manipulating the folding pathway of delta F508 CFTR using chemical chaperones.Semantic proximity Read ↗

Structure basis of CFTR folding, function and pharmacology.Semantic proximity Read ↗

Pharmacological chaperone approaches for rescuing GPCR mutants: Current state, challenges, and screening strategies.Semantic proximity Read ↗

Rescue of Rare CFTR Trafficking Mutants Highlights a Structural Location-Dependent Pattern for Correction.Semantic proximity Read ↗

Rare Trafficking CFTR Mutations Involve Distinct Cellular Retention Machineries and Require Different Rescuing Strategies.Semantic proximity Read ↗

Identification of novel F508del-CFTR traffic correctors among triazole derivatives.Semantic proximity Read ↗

Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis.Semantic proximity Read ↗

Mechanism-based corrector combination restores ΔF508-CFTR folding and function.Semantic proximity Read ↗

Chemical chaperones: a pharmacological strategy for disorders of protein folding and trafficking.Semantic proximity Read ↗

Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small moleculesSemantic proximity Read ↗

Correctors Rescue CFTR Mutations in Nucleotide-Binding Domain 1 (NBD1) by Modulating Proteostasis.Semantic proximity Read ↗

Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.