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Article

Enhancement of xylitol production by attenuation of intracellular xylitol dehydrogenase activity in Candida tropicalis.

Biotechnology letters - 1 Jun 2011

Ko Byoung Sam, Kim Dong-Min, Yoon Byoung Hoon, Bai Suk, Lee Hyeon Yong, Kim Jung Hoe, Kim Il-Chul

Abstract excerpt

To construct Candida tropicalis strains that produce a high yield of xylitol with no requirement for co-substrates, we engineered the yeast with an attenuated xylitol dehydrogenase (XDH) and then assessed the efficiency of xylitol production The mutants, strains XDH-5 (with only one copy of the XDH gene), and ARSdR-16 (with a mutated XDH gene) showed 70 and 40% of wild type (WT) XDH activity, respectively....

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Source

Identifiers

PMID: 21331586
DOI: 10.1007/s10529-011-0558-z

Genes

XDH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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