Article
Cellular prion proteins in human platelets show a phenotype different to those in brain tissues.
Journal of cellular biochemistry - 1 Mar 2011
Kuczius Thorsten, Kleinert Julia, Karch Helge, Sibrowski Walter, Kelsch Reinhard
Abstract excerpt
Prion diseases are characterized by high accumulation of infectious prion proteins (PrP(Sc)) in brains. PrP(Sc) are propagated by the conversion of host-encoded cellular prion proteins (PrP(C)) which are essential for developing the disease but are heterogeneously expressed in brains. The disease can be transmitted to humans and animals through blood and blood products, however, little attention has been given to...
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