Article
Phenotype accessibility and noise in random threshold gene regulatory networks.
PloS one - 1 Jan 2014
Pinho Ricardo, Garcia Victor, Feldman Marcus W
Abstract excerpt
Evolution requires phenotypic variation in a population of organisms for selection to function. Gene regulatory processes involved in organismal development affect the phenotypic diversity of organisms. Since only a fraction of all possible phenotypes are predicted to be accessed by the end of development, organisms may evolve strategies to use environmental cues and noise-like fluctuations to produce additional...
Topics
- Gene Expression
- Gene Regulatory Networks
- Genome
- Models, Genetic
- Phenotype
