Article
Epigenetics meets endocrinology.
Journal of molecular endocrinology - 1 Feb 2011
Zhang Xiang, Ho Shuk-Mei
Abstract excerpt
Although genetics determines endocrine phenotypes, it cannot fully explain the great variability and reversibility of the system in response to environmental changes. Evidence now suggests that epigenetics, i.e. heritable but reversible changes in gene function without changes in nucleotide sequence, links genetics and environment in shaping endocrine function. Epigenetic mechanisms, including DNA methylation,...
Topics
- Animals
- Calcitriol
- DNA Methylation
- Endocrine Disruptors
- Endocrine Glands
- Endocrine System Diseases
- Epigenesis, Genetic
- Gonadal Steroid Hormones
- Histones
- Humans
- MicroRNAs
- Peptide Hormones
