Article
Can brain damage protect against schizophrenia? A case report of twins.
The British journal of psychiatry : the journal of mental science - 1 Oct 1990
Lewis S W, Harvey I, Ron M, Murray R, Reveley A
Abstract excerpt
In a pair of male monozygotic twins discordant for schizophrenia, MRI revealed no abnormality in the ill proband, but extensive white-matter damage of likely congenital origin in the psychiatrically normal twin. These findings are difficult to reconcile with multifactorial models of schizophrenia, and raise the possibility that some forms of brain damage may preclude expression of the schizophrenia genotype.
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