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Article

Genetic predisposition to fracture non-union: a case control study of a preliminary single nucleotide polymorphisms analysis of the BMP pathway.

BMC musculoskeletal disorders - 10 Feb 2011

Dimitriou Rozalia, Carr Ian M, West Robert M, Markham Alexander F, Giannoudis Peter V

Abstract excerpt

BACKGROUND: Despite the known multi-factorial nature of atrophic fracture non-unions, a possible genetic predisposition for the development of this complication after long bone fractures remains unknown. This pilot study aimed to address this issue by performing a preliminary SNP analysis of specific genes known to regulate fracture healing. METHODS: A total of fifteen SNPs within four genes of the Bone...

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Identifiers

PMID: 21310029
DOI: 10.1186/1471-2474-12-44
PMCID: PMC3053586

Genes

SMAD6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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