Article
Searching for genes underlying susceptibility to osteoporotic fracture: current progress and future prospect.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Sept 2007
Lei S-F, Jiang H, Deng F-Y, Deng H-W
Abstract excerpt
INTRODUCTION: Osteoporotic fracture (OF) is a public health problem. It is a common practice in the genetics of osteoporosis that bone mineral density (BMD) was studied as a major surrogate phenotype in gene search for risk of OF (ROF) because of their high phenotypic correlation. However, some studies indicate that the genetic correlation between BMD and ROF is very low. This implies that most genes found...
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