Article
Vitamin D receptor gene as a candidate gene for Parkinson disease.
Annals of human genetics - 1 Mar 2011
Butler Megan W, Burt Amber, Edwards Todd L, Zuchner Stephan, Scott William K, Martin Eden R, Vance Jeffery M, Wang Liyong
Abstract excerpt
Vitamin D and vitamin D receptor (VDR) have been postulated as environmental and genetic factors in neurodegeneration disorders including multiple sclerosis (MS), Alzheimer disease (AD), and recently Parkinson disease (PD). Given the sparse data on PD, we conducted a two-stage study to evaluate the genetic effects of VDR in PD. In the discovery stage, 30 tagSNPs in VDR were tested for association with risk as a...
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