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Article

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas.

The Biochemical journal - 1 May 2011

Pellet-Many Caroline, Frankel Paul, Evans Ian M, Herzog Birger, Jünemann-Ramírez Manfred, Zachary Ian C

Abstract excerpt

NRP1 (neuropilin-1) is a co-receptor for members of the VEGF (vascular endothelial growth factor) family in endothelial cells, but is increasingly implicated in signalling induced by other growth factors. NRP1 is expressed in VSMCs (vascular smooth muscle cells), but its function and the mechanisms involved are poorly understood. The present study aimed to determine the role of NRP1 in the migratory response of...

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Source

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Identifiers

PMID: 21306301
DOI: 10.1042/BJ20100580
PMCID: PMC3086270

Genes

NRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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