Article
Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection.
Heredity - 1 Sept 2011
Albert F W, Hodges E, Jensen J D, Besnier F, Xuan Z, Rooks M, Bhattacharjee A, Brizuela L, Good J M, Green R E, Burbano H A, Plyusnina I Z, Trut L, Andersson L, Schöneberg T, Carlborg O, Hannon G J, Pääbo S
Abstract excerpt
The identification of the causative genetic variants in quantitative trait loci (QTL) influencing phenotypic traits is challenging, especially in crosses between outbred strains. We have previously identified several QTL influencing tameness and aggression in a cross between two lines of wild-derived, outbred rats (Rattus norvegicus) selected for their behavior towards humans. Here, we use targeted sequence...
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