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Article

Can a metastatic gene expression profile outperform tumor size as a predictor of occult lymph node metastasis in oral cancer patients?

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2011

Méndez Eduardo, Lohavanichbutr Pawadee, Fan Wenhong, Houck John R, Rue Tessa C, Doody David R, Futran Neal D, Upton Melissa P, Yueh Bevan, Zhao Lue Ping, Schwartz Stephen M, Chen Chu

Abstract excerpt

PURPOSE: To determine the differential gene expression between oral squamous cell carcinoma (OSCC) with and without metastasis to cervical lymph nodes and to assess prediction of nodal metastasis by using molecular features. EXPERIMENTAL DESIGN: We used Affymetrix U133 2.0 plus arrays to compare the tumor genome-wide gene expression of 73 node-positive OSCCs with 40 node-negative OSCCs (≥ 18 months). Multivariate...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21300763
DOI: 10.1158/1078-0432.CCR-10-0175
PMCID: PMC3078996

Genes

FBXO32
REEP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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