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Article

The effects of EBV transformation on gene expression levels and methylation profiles

2 Feb 2011

Abstract excerpt

Epstein-Barr virus (EBV) transformed lymphoblastoid cell lines (LCLs) provide a conveniently accessible and renewable resource for functional genomic studies in humans. The ability to accumulate multidimensional data pertaining to the same individual cell lines, from complete genomic sequences to detailed gene regulatory profiles, further enhances the utility of LCLs as a model system. A lingering concern,...

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Share to Epigenetics and DNA Methylation
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PMID: 21289059
DOI: 10.1093/hmg/ddr041

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