A validation of the first genome-wide association study of calcaneus ultrasound parameters in the European Male Ageing Study.

doi:10.1186/1471-2350-12-19

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Article

A validation of the first genome-wide association study of calcaneus ultrasound parameters in the European Male Ageing Study.

BMC medical genetics - 28 Jan 2011

Roshandel Delnaz, Thomson Wendy, Pye Stephen R, Boonen Steven, Borghs Herman, Vanderschueren Dirk, Huhtaniemi Ilpo T, Adams Judith E, Ward Kate A, Bartfai Gyorgy, Casanueva Felipe, Finn Joseph D, Forti Gianni, Giwercman Aleksander, Han Thang S, Kula Krzysztof, Lean Michael E, Pendleton Neil, Punab Margus, Silman Alan J, Wu Frederick C, Holliday Kate L, O'Neill Terence W

Abstract excerpt

BACKGROUND: A number of single nucleotide polymorphisms (SNPs) have been associated with broadband ultrasound attenuation (BUA) and speed of sound (SOS) as measured by quantitative ultrasound (QUS) at the calcaneus in the Framingham 100K genome-wide association study (GWAS) but have not been validated in independent studies. The aim of this analysis was to determine if these SNPs are associated with QUS...

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PMID: 21276240
DOI: 10.1186/1471-2350-12-19
PMCID: PMC3042372

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AKAP11

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