Genetic variation in sex hormone genes influences heel ultrasound parameters in middle-aged and elderly men: results from the European Male Aging Study (EMAS).

doi:10.1359/jbmr.080912

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Article

Genetic variation in sex hormone genes influences heel ultrasound parameters in middle-aged and elderly men: results from the European Male Aging Study (EMAS).

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 2009

Limer Kate L, Pye Stephen R, Thomson Wendy, Boonen Steven, Borghs Herman, Vanderschueren Dirk, Huhtaniemi Ilpo T, Adams Judith E, Ward Kate A, Platt Hazel, Payne Debbie, John Sally L, Bartfai Gyorgy, Casanueva Felipe, Finn Joseph D, Forti Gianni, Giwercman Aleksander, Han Thang S, Kula Krzysztof, Lean Michael E, Pendleton Neil, Punab Margus, Silman Alan J, Wu Frederick C, O'Neill Terence W

Abstract excerpt

Genes involved in sex hormone pathways are candidates for influencing bone strength. Polymorphisms in these genes were tested for association with heel quantitative ultrasound (QUS) parameters in middle-aged and elderly European men. Men 40-79 yr of age were recruited from population registers in eight European centers for the European Male Aging Study (EMAS). Polymorphisms were genotyped in AR, ESR1, ESR2,...

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Identifiers

PMID: 18767927
DOI: 10.1359/jbmr.080912

Genes

ESR1
LHCGR
ESR2
LHB
SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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