Article
Cloning and molecular characterization of a metabolic gene with development functions in Drosophila. I. Analysis of the head function of Punch.
Genetics - 1 Dec 1990
McLean J R, Boswell R, O'Donnell J
Abstract excerpt
In an effort to understand the functions of pterins throughout development we have been studying Punch (Pu), the structural gene for the enzyme GTP cyclohydrolase in Drosophila melanogaster. This enzyme catalyzes the first step in the pterin biosynthetic pathway. The Pu gene product is required f...
Topics
- Animals
- Blotting, Southern
- Cloning, Molecular
- Drosophila melanogaster
- Eye Color
- GTP Cyclohydrolase
- Gene Expression Regulation
- Genes
- Mutation
- Nucleic Acid Hybridization
- Pigmentation
- Protein Biosynthesis
- Pterins
- Restriction Mapping
- Transcription, Genetic