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Article

Cloning and molecular characterization of a metabolic gene with development functions in Drosophila. I. Analysis of the head function of Punch.

Genetics - 1 Dec 1990

McLean J R, Boswell R, O'Donnell J

Abstract excerpt

In an effort to understand the functions of pterins throughout development we have been studying Punch (Pu), the structural gene for the enzyme GTP cyclohydrolase in Drosophila melanogaster. This enzyme catalyzes the first step in the pterin biosynthetic pathway. The Pu gene product is required for vital functions at two distinct stages in embryogenesis, and a pigmentation function in the eye of the young adult....

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Identifiers

PMID: 2127575
DOI: 10.1093/genetics/126.4.1007
PMCID: PMC1204265

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